The seeds of this beautiful tree contain aescin, a widely used anti-inflammatory agent for a variety of condition, in addition to being used for vascular problems. There is ample evidence supporting the usage of Horse Chestnut to treat varicose veins and inflammatory disorders of the legs. Many animal experiments have repeatedly confirmed the anti-inflammatory and anti-edema action of aescin. Dosage is one capsule twice a day with water and meals. 90 Capsules 20% aescin.